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C87619Level 5

Linogliride Fumarate

**Semantic type:** Pharmacologic Substance

**Definition:** The fumarate salt form of linogliride, a guanidine-based insulin secratogogue and structural analogue of pirogliride with hypoglycemic activity. Linogliride blocks ATP-sensitive potassium channels on the membranes of pancreatic beta cells which stimulates the secretion of insulin and improves glucose tolerance.

**Synonyms:** - LINOGLIRIDE FUMARATE - MCN-3935

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