Fezakinumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A human monoclonal antibody directed against interleukin-22 (IL-22) with anti-inflammatory activity. Fezakinumab binds to IL-22 and prevents the activity of this interleukin. This leads to an inhibition of inflammation. IL-22, a cytokine and member of the IL-10 superfamily, plays a key role during inflammatory responses.

**Synonyms:** - FEZAKINUMAB - ILV-094 - Immunoglobulin G1, Anti-(Human Interleukin 22) (Human Monoclonal Heavy Chain), Disulfide with Human Monoclonal Lambda-Chain, Dimer - Immunoglobulin G1, Anti-(Human/Macaca irus/Rattus/Mus musculus Interleukin 22) (Human Monoclonal Heavy Chain), Disulfide with Human Monoclonal Lambda-Chain, Dimer