NEFL wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NEFL wild-type allele is located in the vicinity of 8p21 and is approximately 6 kb in length. This allele, which encodes neurofilament light polypeptide protein, plays a role in both the establishment and maintenance of axonal and dendritic structures. Mutation of the gene is associated with Charcot-Marie-Tooth disease types 1F and 2E.

**Synonyms:** - CMT1F - CMT2E - CMTDIG - FLJ53642 - NF-L - NF68 - NFL - Neurofilament Light Chain wt Allele - Neurofilament Light Gene - Neurofilament Protein, Light Chain Gene - Neurofilament Protein, Light Polypeptide Gene - Neurofilament, Light Polypeptide 68kDa Gene - Neurofilament, Light Polypeptide Gene - PPP1R110 - Protein Phosphatase 1, Regulatory Subunit 110 Gene