YWHAZ wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human YWHAZ wild-type allele is located in the vicinity of 8q23.1 and is approximately 35 kb in length. This allele, which encodes 14-3-3 protein zeta/delta, plays a role in signal transduction. Amplification of the gene may be associated with both anthracycline resistance and metastatic recurrence in breast cancer.

**Synonyms:** - 14-3-3 zeta - 14-3-3-zeta - KCIP-1 - MGC111427 - MGC126532 - MGC138156 - Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Zeta Polypeptide wt Allele