LAPTM4B wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LAPTM4B wild-type allele is located in the vicinity of 8q22.1 and is approximately 146 kb in length. This allele, which encodes lysosomal-associated transmembrane protein 4B, may be involved in transport. Amplification of the gene may be associated with hepatocellular carcinoma and both anthracycline resistance and metastatic recurrence in breast cancer.

**Synonyms:** - LAPTM4beta - LC27 - Lysosomal Protein Transmembrane 4 Beta wt Allele