Ramosetron Hydrochloride

**Semantic type:** Pharmacologic Substance

**Definition:** The hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity. Upon administration, ramosetron selectively binds to and blocks the activity of 5-HT subtype 3 (5-HT3) receptors located in the vagus nerve terminal and in the vomiting center in the central nervous system (CNS), suppressing chemotherapy-induced nausea and vomiting.

**Synonyms:** - (R)-5-((1-Methyl-3-indolyl)carbonyl)-4,5,6,7-tetrahydro-1H-benzimidazole Hydrochloride - Irribow - Nasea - RAMOSETRON HYDROCHLORIDE - YM-060