CST3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CST3 wild-type allele is located in the vicinity of 20p11.21 and is approximately 4 kb in length. This allele, which encodes cystatin-C protein, plays a role in the regulation of cysteine protease activity. Mutation of the gene is associated with both amyloidosis type 6 and age-related macular degeneration type 11.

**Synonyms:** - ARMD11 - Cystatin C (Amyloid Angiopathy and Cerebral Hemorrhage) Gene - Cystatin C wt Allele - MGC117328