Motavizumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A humanized monoclonal antibody directed against the respiratory syncytial virus (RSV) fusion glycoprotein (F-protein), with activity against RSV. Motavizumab targets and binds to the RSV F-protein, which prevents F-protein-mediated RSV fusion with human host cells. This protects against RSV infection. RSV F-protein mediates RSV attachment and fusion to host cells.

**Synonyms:** - Immunoglobulin G1, anti-(respiratory syncytial virus glocoprotein F) (human-mouse monoclonal MEDI-524 gamma-1-chain), disulfide with human-mouse monoclonal MEDI-524 kappa-chain, dimer - MEDI-524 - MOTAVIZUMAB