DCLRE1C wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DCLRE1C wild-type allele is located in the vicinity of 10p13 and is approximately 97 kb in length. This allele, which encodes protein artemis, plays a role in the mediation of both V(D)J recombination and DNA repair via nonhomologous end joining. Mutation of the gene is associated with severe combined immunodeficiency Athabaskan type and Omenn syndrome.

**Synonyms:** - A-SCID - ARTEMIS - ASCID - DCLREC1C - DNA Cross-Link Repair 1C (PSO2 Homolog, S. cerevisiae) Gene - DNA Cross-Link Repair 1C wt Allele - FLJ11360 - FLJ36438 - OTTHUMP00000019166 - OTTHUMP00000019167 - OTTHUMP00000019168 - OTTHUMP00000019170 - OTTHUMP00000019171 - OTTHUMP00000019172 - PSO2 Homolog Gene - RS-SCID - SCIDA - SNM1C - Severe Combined Immunodeficiency, Type a (Athabascan) Gene - hSNM1C