MYD88 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MYD88 wild-type allele is located in the vicinity of 3p22 and is approximately 5 kb in length. This allele, which encodes myeloid differentiation primary response protein MyD88, plays a role in both protein-protein interactions and the regulation of the expression of proinflammatory genes. Mutation of the gene is associated with recurrent pyogenic bacterial infections.

**Synonyms:** - MYD88D - Myeloid Differentiation Primary Response 88 wt Allele - Myeloid Differentiation Primary Response Gene (88) - Myeloid Differentiation Primary Response Gene 88