SNCA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SNCA wild-type allele is located in the vicinity of 4q21 and is approximately 111 kb in length. This allele, which encodes alpha-synuclein protein, is involved in presynaptic signaling and membrane trafficking. Mutation of the gene is associated with Alzheimer disease, Parkinson disease and Lewy body dementia.

**Synonyms:** - Alpha-Synuclein Gene - MGC110988 - NACP - PARK1 - PARK4 - PD1 - Synuclein, Alpha (Non A4 Component of Amyloid Precursor) wt Allele