CTSK wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CTSK wild-type allele is located in the vicinity of 1q21 and is approximately 12 kb in length. This allele, which encodes cathepsin K protein, plays a role in the regulation of both proteolysis and osteoclastic bone resorption. Mutation of the gene is associated with pycnodysostosis.

**Synonyms:** - CTS02 - CTSO - CTSO1 - CTSO2 - Cathepsin K (Pycnodysostosis) Gene - Cathepsin K wt Allele - Cathepsin O1 Gene - MGC23107 - PKND - PYCD