COMMD1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human COMMD1 wild-type allele is located in the vicinity of 2p15 and is approximately 388 kb in length. This allele, which encodes COMM domain-containing protein 1, plays a role in the modulation of NF-kappa-B signaling, copper homeostasis and sodium uptake. The gene is aberrantly expressed in many tumors.

**Synonyms:** - C2orf5 - Chromosome 2 Open Reading Frame 5 (MURR1) Gene - Copper Metabolism (Murr1) Domain Containing 1 wt Allele - Copper Metabolism Gene MURR1 Gene - MGC27155 - MURR1