Octimibate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor with antilipidemic, antiatherosclerotic, and antithrombotic activity. In an animal model, inhibition of ACAT by octimibate increased HDL receptor activity and stimulated HDL-mediated cholesterol efflux from peritoneal macrophages.

**Synonyms:** - OCTIMIBATE