Breast Medullary Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** An infiltrating breast carcinoma with a relatively favorable prognosis. It is an uncommon carcinoma, accounting for less than 1% of all infiltrating breast carcinomas. It is well circumscribed, with soft cut surface and often of considerable size. Microscopically, the predominant growth pattern is syncytial with broad anastomosing bands or sheets of malignant cells. The malignant cells are round with abundant cytoplasm and vesicular nuclei. The sheets of malignant cells are associated with a marked lymphoplasmacytic infiltrate. Glandular or tubular structures are absent.

**Synonyms:** - Infiltrating Medullary Carcinoma of Breast - Infiltrating Medullary Carcinoma of the Breast - Invasive Medullary Breast Carcinoma - Invasive Medullary Carcinoma of Breast - Invasive Medullary Carcinoma of the Breast - Medullary Breast Cancer - Medullary Breast Carcinoma - Medullary Breast Carcinoma with Lymphoid Stroma - Medullary Carcinoma of Breast - Medullary Carcinoma of the Breast - Medullary carcinoma with lymphoid stroma - medullary breast carcinoma