F5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human F5 wild-type allele is located in the vicinity of 1q23 and is approximately 75 kb in length. This allele, which encodes coagulation factor V protein, is involved in the mediation of coagulation. Mutation of the gene is associated with hemorrhagic diathesis in factor V deficiency, Budd-Chiari syndrome, thrombophilia due to activated protein C resistance and susceptibility to ischemic stroke.

**Synonyms:** - Coagulation Factor V (Proaccelerin, Labile Factor) Gene - Coagulation Factor V wt Allele - PCCF - RPRGL1 - THPH2