mTOR Signaling Pathway KEGG

**Semantic type:** Functional Concept

**Definition:** A set of complex signal transduction pathways described by the Kyoto Encyclopedia of Genes and Genomes (KEGG) Pathway database, where each is dependent on the protein kinase activity of serine/threonine-protein kinase mTOR. This kinase is part of 2 structurally and functionally distinct signaling complexes, mTOR complex 1 and 2 (mTORC1 and mTORC2, respectively), which together regulate cellular metabolism, growth and survival in response to hormones, growth factors, nutrients and stress signals.

**Synonyms:** - mTOR Signaling Pathway - mTOR signaling pathway