SIAH2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SIAH2 wild-type allele is located in the vicinity of 3q25 and is approximately 22 kb in length. This allele, which encodes E3 ubiquitin-protein ligase SIAH2 protein, is involved in the mediation of ubiquitination. Expression of the gene may play a role in the development or progression of metastatic prostate neuroendocrine tumor.

**Synonyms:** - Seven in Absentia Homolog 2 (Drosophila)wt Allele - hSiah2