TBX5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TBX5 wild-type allele is located in the vicinity of 12q24.1 and is approximately 55 kb in length. This allele, which encodes T-box transcription factor TBX5 protein, plays a role in both transcription and mesoderm differentiation. Mutation of the gene is associated with Holt-Oram syndrome.

**Synonyms:** - HOS - T-Box 5 wt Allele