FOXD3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FOXD3 wild-type allele is located within 1p32-p31 and is approximately 2 kb in length. This allele, which encodes forkhead box protein D3, plays a role in the regulation of transcription, neural tube differentiation and pluripotent stem cell maintenance during embryogenesis. Mutation of the gene is associated with autoimmune disease type 1.

**Synonyms:** - AIS1 - Forkhead Box D3 wt Allele - Genesis - HFH2