Hereditary Papillary Renal Cell Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** A familial carcinoma inherited in an autosomal dominant trait. It is characterized by the development of multiple, bilateral papillary renal cell carcinomas. The carcinomas range from microscopic lesions to clinically symptomatic tumors. It is associated with activating mutations of the MET oncogene.

**Synonyms:** - Familial Renal Papillary Carcinoma - Hereditary Kidney Papillary Carcinoma - Hereditary Papillary Carcinoma of Kidney - Hereditary Papillary Carcinoma of the Kidney - Hereditary Papillary Renal Carcinoma - Hereditary Papillary Renal Cell Cancer