FANCL wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FANCL wild-type allele is located in the vicinity of 2p16.1 and is approximately 82 kb in length. This allele, which encodes E3 ubiquitin-protein ligase FANCL protein, plays a role in the modulation of both protein ubiquitination and Fanconi anemia complex-mediated DNA repair. Mutation of the gene is associated with Fanconi anemia.

**Synonyms:** - FA Complementation Group L wt Allele - FAAP43 - FLJ10335 - Fanconi Anemia Complementation Group L Gene - Fanconi Anemia, Complementation Group L Gene - PHD Finger Protein 9 Gene - PHF9 - POG