Vindesine Sulfate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The sulfate salt form of Vindesine. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI)

**Synonyms:** - Desacetyl Vinblastine Amide Sulfate - Eldesine - Eldisin - Eldisine - Enison - Fildesin - Gesidine - LY 099094 - LY-099094 - LY099094 - VINDESINE SULFATE - Vindesine Sulphate - Vindesine sulfate - Vindesini Sulfas