PDCD1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PDCD1 wild-type allele is located in the vicinity of 2q37.3 and is approximately 9 kb in length. This allele, which encodes programmed cell death protein 1, plays a role in the modulation of both apoptosis and cellular immunity. Mutation of the gene is associated with systemic lupus erythematosus type 2.

**Synonyms:** - CD279 - PD-1 - PD1 - Programmed Cell Death 1 wt Allele - SLEB2 - Systemic Lupus Erythematosus Susceptibility 2 Gene - hPD-1 - hPD-l - hSLE1