Azidocillin Potassium

**Semantic type:** Antibiotic|Pharmacologic Substance

**Definition:** The potassium salt of a narrow-spectrum, semisynthetic penicillin derivative with antibacterial activity. Azidocillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.

**Synonyms:** - 4-Thia-1-Azabicyclo(3.2.0)Heptane-2-Carboxylic Acid,6-((Azidophenylacetyl)Amino)-3,3-Dimethyl-7-Oxo-, Monopotassium Salt, (2s-(2Alpha,5Alpha,6Beta(S*)))- - AZIDOCILLIN POTASSIUM - D-(-)-Alpha-Azidobenzylpenicillin Potassium Salt