LRP8 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LRP8 wild-type allele is located in the vicinity of 1p34 and is approximately 83 kb in length. This allele, which encodes low-density lipoprotein receptor-related protein 8, is involved in signal transduction, neuronal development, ligand endocytosis and lipid metabolism. Mutation of the gene is associated with myocardial infarction type 1.

**Synonyms:** - APOER2 - HSZ75190 - Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor wt Allele - MCI1