Ancrod

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A proteolytic enzyme and defibrinogenating agent derived from the venom of the Malayan pit viper, with profibrinolytic and anticoagulant activities. Upon administration, ancrod cleaves fibrinogen and releases A-fibrinopeptides. This inactivates fibrinogen and leads to a reduction in blood viscosity, increases blood flow and perfusion of the microcirculation.

**Synonyms:** - ANCROD - Abbott 38414 - Acc-C - Agkistrododon Protein C Activator - Agkistrododon Rhodostoma Venom Proteinase - Arvin - Arwin - Brevinase - Proteinase, Agkistrodon Serine - Venacil - Venombin-A - Viprinex