SFRP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SFRP1 wild-type allele is located in the vicinity of 8p11.21 and is approximately 48 kb in length. This allele, which encodes secreted frizzled-related protein 1, plays a role in the modulation of Wnt signaling. Methylation of the gene is associated with decreased expression and may be a factor in both colon and breast cancer.

**Synonyms:** - FRP - FRP-1 - FRP1 - FrzA - SARP2 - Secreted Frizzled-Related Protein 1 wt Allele