LRP6 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LRP6 wild-type allele is located in the vicinity of 12p13.2 and is approximately 151 kb in length. This allele, which encodes low-density lipoprotein receptor-related protein 6, is involved in the mediation of ligand endocytosis and cell communication. Mutation of the gene is associated with autosomal dominant coronary artery disease type 2.

**Synonyms:** - ADCAD2 - FLJ90062 - FLJ90421 - LDL Receptor Related Protein 6 wt Allele - Low Density Lipoprotein Receptor-Related Protein 6 Gene