MAML2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MAML2 wild-type allele is located in the vicinity of 11q21 and is approximately 365 kb in length. This allele, which encodes mastermind-like protein 2, is involved in the modulation of Notch signaling-dependent gene expression. A translocation t(11;19)(q21;p13) involving this gene and the CRTC1 gene is associated with mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas.

**Synonyms:** - DKFZp686N0150 - KIAA1819 - MAM-3 - MAM2 - MAM3 - MGC176701 - MLL-MAML2 - Mastermind Like Transcriptional Coactivator 2 wt Allele - Mastermind-Like 2 (Drosophila) Gene