UROD wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human UROD wild-type allele is located in the vicinity of 1p34 and is approximately 4 kb in length. This allele, which encodes uroporphyrinogen decarboxylase protein, plays a role in the regulation of heme biosynthesis. Mutation of the gene is associated with both familial porphyria cutanea tarda and hepatoerythropoietic porphyria.

**Synonyms:** - PCT - UPD - Uroporphyrinogen Decarboxylase wt Allele - Uroporphyrinogen III Decarboxylase Gene