Anrukinzumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A humanized monoclonal antibody directed against interleukin-13 (IL-13) with anti-asthmatic and anti-inflammatory activities. Anrukinzumab binds to and blocks the activity of IL-13, which may result in the inhibition of IL-13-mediated inflammation. The IL-13 cytokine is an important mediator of allergic inflammation and other inflammatory processes.

**Synonyms:** - ANRUKINZUMAB - IMA-638 - Immunoglobulin G1, anti-(human interleukin-13) Humanized Mouse Monoclonal Gamma 1 Heavy Chain 235L>A, 238G>A (221-218')-disulfide with Humanized Mouse Monoclonal Kappa Light Chain (227-227'':230-230'')-bisdisulfide Dimer