PIGA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PIGA wild-type allele is located in the vicinity of Xp22.1 and is approximately 16 kb in length. This allele, which encodes phosphatidylinositol N-acetylglucosaminyltransferase subunit A protein, plays a role in the modulation of protein lipidation. Mutation of the gene is associated with paroxysmal nocturnal hemoglobinuria.

**Synonyms:** - GPI3 - MCAHS2 - PIG-A - PNH1 - Paroxysmal Nocturnal Hemoglobinuria Gene - Phosphatidylinositol Glycan Anchor Biosynthesis Class A wt Allele - Phosphatidylinositol Glycan Anchor Biosynthesis, Class A Gene - Phosphatidylinositol Glycan, Class A (Paroxysmal Nocturnal Hemoglobinuria) Gene