Ampulla of Vater Mixed Adenoneuroendocrine Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** A carcinoma that arises from the ampulla of Vater and the periampullary region. It is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component. At least 30 percent of either component should be present for the diagnosis to be made.

**Synonyms:** - Ampulla of Vater MANEC