NR4A3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NR4A3 wild-type allele is located in the vicinity of 9q22 and is approximately 45 kb in length. This allele, which encodes nuclear receptor subfamily 4 group A member 3 protein, plays a role in the regulation of gene expression. Translocation t(9;22)(q22-31;q11-12) involving the NR4A3 gene and the EWSR1 gene is associated with Ewing sarcoma and translocation t(9;17)(q22;q11) involving the NR4A3 gene and the TAF15 gene is associated with extraskeletal myxoid chondrosarcoma.

**Synonyms:** - CHN - CSMF - Chondrosarcoma, Extraskeletal Myxoid, Fused to EWS Gene - Chondrosarcoma, Myxoid Extraskeletal, Fused to EWS Gene - MINOR - NOR1 - Nuclear Receptor Subfamily 4 Group A Member 3 wt Allele - Nuclear Receptor Subfamily 4, Group A, Member 3 Gene - RP11-60I3.3 - TEC - Translocated In Extraskeletal Chondrosarcoma Gene