CFLAR wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CFLAR wild-type allele is located within 2q33-q34 and is approximately 48 kb in length. This allele, which encodes CASP8 and FADD-like apoptosis regulator protein, is involved in the modulation of caspase-mediated apoptosis and proteolysis.

**Synonyms:** - CASH - CASP8 and FADD-Like Apoptosis Regulator wt Allele - CASP8AP1 - CLARP - Caspase-Related Inducer of Apoptosis Gene - Casper - FLAME - FLAME-1 - FLAME1 - FLIP - I-FLICE - MRIT - c-FLIP - c-FLIPL - c-FLIPR - c-FLIPS