MOPP Regimen

**Semantic type:** Therapeutic or Preventive Procedure

**Definition:** A regimen consisting of mechlorethamine, vincristine (Oncovin), procarbazine and prednisone, used alone or in combination with radiation therapy for the treatment of stage I-IV Hodgkin lymphoma. Due to the increased risk of gonadal toxicity, this regimen has been widely replaced by the ABVD regimen.

**Synonyms:** - MOPP - MOPP - MOPP - MOPP regimen - Mechlorethamine/Prednisone/Procarbazine/Vincristine Regimen - Mustargen-Oncovin-Procarbazine-Prednisone Regimen - NM/PCB/PRED/VCR