ALOX12B wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ALOX12B wild-type allele is located in the vicinity of 17p13.1 and is approximately 15 kb in length. This allele, which encodes arachidonate 12-lipoxygenase, 12R-type protein, plays a role in arachidonic acid metabolism. Mutation of the gene is associated with non-bullous congenital ichthyosiform erythroderma.

**Synonyms:** - 12R-LOX - Arachidonate 12-Lipoxygenase, 12R Type wt Allele