NSD3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NSD3 wild-type allele is located in the vicinity of 8p11.23 and is approximately 113 kb in length. This allele, which encodes histone-lysine N-methyltransferase NSD3 protein, plays a role in the regulation of histone methylation. A chromosomal translocation t(8;11)(p11;p15) involving the NUP98 gene and this gene is associated with acute myeloid leukemia.

**Synonyms:** - DC28 - DKFZp667H044 - FLJ20353 - KMT3F - KMT3G - MGC126766 - MGC142029 - Nuclear Receptor Binding SET Domain Protein 3 wt Allele - WHISTLE - WHSC1L1 - Wolf-Hirschhorn Syndrome Candidate 1-Like 1 Gene - pp14328