MUTYH-Associated Polyposis

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal recessive hereditary neoplastic syndrome caused by mutations in the MUTYH gene on chromosome 1p34.1. It is characterized by the presence of multiple colorectal polyps that may progress to carcinoma. Development of gastric and small intestinal polyps may also occur.

**Synonyms:** - MAP - MYH-Associated Polyposis