PIK3CA Gene Amplification

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A molecular genetic abnormality indicating the presence of multiple copies of the PIK3CA (phosphatidyl inositol 3-kinase) gene.

**Synonyms:** - PI3K Gene Amplification - PI3K-Alpha Gene Amplification - PI3KCA Gene Amplification - PIK3-Alpha Gene Amplification - Phosphatidylinositol 3-Kinase, Catalytic Subunit Gene Amplification - Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Gene Amplification - Phosphoinositide-3-Kinase, Catalytic, Alpha Polypeptide Gene Amplification - p110-Alpha Gene Amplification