Clopidogrel Hydrochloride

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The hydrochloride salt form of clopidogrel, a thienopyridine, with antiplatelet activity. Clopidogrel targets, irreversibly binds to and alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time.

**Synonyms:** - CLOPIDOGREL HYDROCHLORIDE - Clopidogrel HCl - Thieno(3,2-C)Pyridine-5(4h)-Acetic Acid, alpha-(2-Chlorophenyl)-6,7-Dihydro-, Methyl Ester, Hydrochloride, (S)-