RASGRP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RASGRP1 wild-type allele is located in the vicinity of 15q14 and is approximately 77 kb in length. This allele, which encodes RAS guanyl-releasing protein 1, is involved in the modulation of small GTPase activation through its guanine nucleotide exchange activity. Mutation of the gene is associated with systemic lupus erythematosus.

**Synonyms:** - CALDAG-GEFI - CALDAG-GEFII - Guanine Nucleotide Exchange Factor, Calcium- and DAG-Regulated, Rap1A Gene - MGC129998 - MGC129999 - RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) wt Allele - RASGRP - V - hRasGRP1