IRGM wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IRGM wild-type allele is located in the vicinity of 5q33.1 and is approximately 2 kb in length. This allele, which encodes immunity-related GTPase family M protein, plays a role in both GTP metabolism and immune responses. A silent mutation in the gene is associated with increased risk of Crohn disease.

**Synonyms:** - IFI1 - IRGM1 - Immunity-Related GTPase Family, M wt Allele - LRG-47 - LRG47 - MGC149263 - MGC149264