RPN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RPN1 wild-type allele is located in the vicinity of 3q21.3 and is approximately 61 kb in length. This allele, which encodes dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 1 protein, is involved in the regulation of protein glycosylation. A chromosomal aberration, either t(3;3)(q21;q26) or inv(3)(q21q26), of this gene and the MECOM gene is associated with acute myeloid leukemia.

**Synonyms:** - DKFZp686B16177 - OST1 - Oligosaccharyltransferase 1 Homolog (S. cerevisiae) Gene - RBPH1 - Ribophorin I wt Allele