MRTFA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MRTFA wild-type allele is located within 22q13.1-q13.2 and is approximately 226 kb in length. This allele, which encodes myocardin-related transcription factor A protein, plays a role in the positive regulation of both smooth muscle cell differentiation and transcription. A chromosomal translocation t(1;22)(p13;q13) with the RBM15 gene is associated with acute megakaryoblastic leukemia.

**Synonyms:** - BSAC - Basic, SAP and Coiled-Coil Domain Gene - MAL - MKL - MKL1 - MKL1 wt Allele - MRTF-A - Megakaryoblastic Leukemia (Translocation) 1 Gene - Megakaryoblastic Leukemia 1 Gene - Megakaryocytic Acute Leukemia Gene - Myocardin Related Transcription Factor A wt Allele - Myocardin-Related Transcription Factor A Gene - RP5-1042K10.11-009