ASXL1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ASXL1 wild-type allele is located in the vicinity of 20q11 and is approximately 81 kb in length. This allele, which encodes putative Polycomb group protein ASXL1, may play a role in the regulation of both chromatin structure and transcription. Mutation of the gene is associated with both myelodysplastic syndromes and chronic myelomonocytic leukemia.

**Synonyms:** - ASXL Transcriptional Regulator 1 wt Allele - Additional Sex Combs Like 1 (Drosophila) Gene - Additional Sex Combs Like 1, Transcriptional Regulator 1 Gene - BOPS - KIAA0978 - MDS - MGC117280 - MGC71111 - RP11-358N2.1