CARS1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CARS1 wild-type allele is located in the vicinity of 11p15.5 and is approximately 57 kb in length. This allele, which encodes cysteine-tRNA ligase, cytoplasmic protein, plays a role in the metabolism of tRNA. A translocation t(2;11)(p23;p15) of this gene and the ALK gene is associated with inflammatory myofibroblastic tumors.

**Synonyms:** - CARS - CARS wt Allele - CARS1 - CYSRS - Cysteine Translase Gene - Cysteine tRNA Ligase 1, Cytoplasmic Gene - Cysteinyl-tRNA Synthetase 1 wt Allele - Cysteinyl-tRNA Synthetase Gene - MCDDBH - MDBH - MGC:11246