MLLT11 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MLLT11 wild-type allele is located in the vicinity of 1q21 and is approximately 11 kb in length. This allele, which encodes protein AF1q, plays a role in both depolarization of and release of cytochrome c by the mitochondrion. The gene is involved in a translocation t(1;11)(q21;q23) with the MLL gene that is associated with acute leukemia.

**Synonyms:** - AF1Q - AF1q - ALL1 Fused Gene from Chromosome 1q Gene - Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 11 wt Allele - RP11-316M1.10