CLTCL1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CLTCL1 wild-type allele is located in the vicinity of 22q11.2 and is approximately 112 kb in length. This allele, which encodes clathrin heavy chain 2 protein, plays a role in receptor-mediated endocytosis and cellular vesicle transport. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome.

**Synonyms:** - CHC - CHC22 - CLH22 - CLTCL - CLTD - Clathrin Heavy Chain Like 1 wt Allele - Clathrin, Heavy Chain-Like 1 Gene - Clathrin, Heavy Polypeptide D Gene - Clathrin, Heavy Polypeptide-Like 1 Gene - FLJ36032